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human igg concentrations  (Thermo Fisher)


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    Thermo Fisher human igg concentrations
    Human Igg Concentrations, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 2990 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 99 stars, based on 2990 article reviews
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    99/100 stars

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    Seroprevalence and serological profiles of anti-MCPyV IgG antibodies and total IgG concentration in sera. (A) MCPyV seroprevalences were evaluated in PM patients (n=108), WEA (n=102), and HS (n=110). (B,C) Serological profiles of serum antibody reactivity to VP1 S (B), VP2 F (C) peptides evaluated in PM patients, WEA, and HS. Immunologic data are reported as OD value readings at λ 405 nm for sera analyzed in indirect immunoassay. In the scatter dot plot, each dot represents the dispersion of ODs of each sample. The median is indicated by the line inside the scatter plot with the IQR in PM patients, WEA, and HS. (D) Total IgG concentration values in serum samples from PM patients, WEA, and HS, reported as mg/mL. Data are presented as IgG mean values and their ranges marked by short horizontal lines. The dashed line indicates the cut-off value. ****, P<0.0001. HS, healthy subjects; IgG, immunoglobulin G; IQR, interquartile range; MCPyV, Merkel cell polyomavirus; OD, optical density; PM, pleural mesothelioma; VP, viral protein; WEA, workers ex-exposed to asbestos.

    Journal: Translational Lung Cancer Research

    Article Title: Pleural mesothelioma patients and ex-exposed asbestos workers are immunologically poor responders to oncogenic Merkel cell polyomavirus

    doi: 10.21037/tlcr-2025-198

    Figure Lengend Snippet: Seroprevalence and serological profiles of anti-MCPyV IgG antibodies and total IgG concentration in sera. (A) MCPyV seroprevalences were evaluated in PM patients (n=108), WEA (n=102), and HS (n=110). (B,C) Serological profiles of serum antibody reactivity to VP1 S (B), VP2 F (C) peptides evaluated in PM patients, WEA, and HS. Immunologic data are reported as OD value readings at λ 405 nm for sera analyzed in indirect immunoassay. In the scatter dot plot, each dot represents the dispersion of ODs of each sample. The median is indicated by the line inside the scatter plot with the IQR in PM patients, WEA, and HS. (D) Total IgG concentration values in serum samples from PM patients, WEA, and HS, reported as mg/mL. Data are presented as IgG mean values and their ranges marked by short horizontal lines. The dashed line indicates the cut-off value. ****, P<0.0001. HS, healthy subjects; IgG, immunoglobulin G; IQR, interquartile range; MCPyV, Merkel cell polyomavirus; OD, optical density; PM, pleural mesothelioma; VP, viral protein; WEA, workers ex-exposed to asbestos.

    Article Snippet: Total serum IgG concentration was determined using the human IgG total enzyme-linked immunosorbent assay (ELISA) kit (Thermo, Milan, Italy).

    Techniques: Concentration Assay, Dispersion

    OS analysis, seroprevalence and serological profiles of anti-MCPyV IgG antibodies evaluated in PM patients, and total IgG concentration in sera. (A) Kaplan-Meier model was used to longitudinally evaluate an association between MCPyV seropositivity and PM (n=108) patient’s OS during 99 months follow up. No significant differences were observed between MCPyV-seropositive and seronegative PMs (P>0.05). (B) Seroprevalences were compared in epithelioid (n=40), sarcomatoid (n=24), and biphasic (n=43) PM histotypes. (C,D) Serological profiles of serum antibody reactivity to VP1 S (C) and VP2 F (D) peptides were evaluated in the three PM histotypes. Immunologic data are reported as OD value readings at λ 405 nm for sera analyzed in immunoassay. In the scatter dot plot, each dot represents the dispersion of ODs of each sample. The median is indicated by the line inside the scatter plot with the IQR in PM epithelioid (n=40), sarcomatoid (n=24), and biphasic (n=43). (E) Total IgG concentration values in serum samples from CaP-PM (n=19), M-PM (n=11), P-PM (n=8), CiP-PM (n=5), and no-PM (n=17), reported as mg/mL. Data are presented as IgG mean values and their ranges marked by short horizontal lines. (F) Seroprevalences were compared in PM patients under CaP-PM (n=19), M-PM (n=11), P-PM (n=8), CiP-PM (n=5), and no-PM (n=17). (G,H) Serological profiles of serum antibody reactivity to VP1 S (G) and VP2 F (H) peptides were evaluated in PM patients undergoing different therapeutic regimens. (C,D,G,H) Immunologic data are reported as OD value readings at λ 405 nm for sera analyzed in immunoassay. In the scatter dot plot, each dot represents the dispersion of ODs of each sample. The dashed line indicates the cut-off value. *, P<0.05; ***, P<0.001. CaP-PM, PM patients under carboplatin + pemetrexed; CiP-PM, PM patients under cisplatin + pemetrexed; IgG, immunoglobulin G; IQR, interquartile range; M-PM, PM patients under mixed therapy; MCPyV, Merkel cell polyomavirus; no-PM, PM patients under no chemotherapy; OD, optical density; OS, overall survival; P-PM, PM patients under pemetrexed alone; PM, pleural mesothelioma; VP, viral protein.

    Journal: Translational Lung Cancer Research

    Article Title: Pleural mesothelioma patients and ex-exposed asbestos workers are immunologically poor responders to oncogenic Merkel cell polyomavirus

    doi: 10.21037/tlcr-2025-198

    Figure Lengend Snippet: OS analysis, seroprevalence and serological profiles of anti-MCPyV IgG antibodies evaluated in PM patients, and total IgG concentration in sera. (A) Kaplan-Meier model was used to longitudinally evaluate an association between MCPyV seropositivity and PM (n=108) patient’s OS during 99 months follow up. No significant differences were observed between MCPyV-seropositive and seronegative PMs (P>0.05). (B) Seroprevalences were compared in epithelioid (n=40), sarcomatoid (n=24), and biphasic (n=43) PM histotypes. (C,D) Serological profiles of serum antibody reactivity to VP1 S (C) and VP2 F (D) peptides were evaluated in the three PM histotypes. Immunologic data are reported as OD value readings at λ 405 nm for sera analyzed in immunoassay. In the scatter dot plot, each dot represents the dispersion of ODs of each sample. The median is indicated by the line inside the scatter plot with the IQR in PM epithelioid (n=40), sarcomatoid (n=24), and biphasic (n=43). (E) Total IgG concentration values in serum samples from CaP-PM (n=19), M-PM (n=11), P-PM (n=8), CiP-PM (n=5), and no-PM (n=17), reported as mg/mL. Data are presented as IgG mean values and their ranges marked by short horizontal lines. (F) Seroprevalences were compared in PM patients under CaP-PM (n=19), M-PM (n=11), P-PM (n=8), CiP-PM (n=5), and no-PM (n=17). (G,H) Serological profiles of serum antibody reactivity to VP1 S (G) and VP2 F (H) peptides were evaluated in PM patients undergoing different therapeutic regimens. (C,D,G,H) Immunologic data are reported as OD value readings at λ 405 nm for sera analyzed in immunoassay. In the scatter dot plot, each dot represents the dispersion of ODs of each sample. The dashed line indicates the cut-off value. *, P<0.05; ***, P<0.001. CaP-PM, PM patients under carboplatin + pemetrexed; CiP-PM, PM patients under cisplatin + pemetrexed; IgG, immunoglobulin G; IQR, interquartile range; M-PM, PM patients under mixed therapy; MCPyV, Merkel cell polyomavirus; no-PM, PM patients under no chemotherapy; OD, optical density; OS, overall survival; P-PM, PM patients under pemetrexed alone; PM, pleural mesothelioma; VP, viral protein.

    Article Snippet: Total serum IgG concentration was determined using the human IgG total enzyme-linked immunosorbent assay (ELISA) kit (Thermo, Milan, Italy).

    Techniques: Concentration Assay, Dispersion